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KMID : 1037420180130010044
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Journal of Korean Skull Base Society
2018 Volume.13 No. 1 p.44 ~ p.48
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Nasopharyngeal pleomorphic adenoma mimicking squamous cell carcinoma: report of 2 cases and review of the literature
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Ryu Gwang-Hui
Hong Sang-Duk
Chung Seung-Kyu
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Abstract
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Pleomorphic adenoma (PA) of nasopharynx is very rare. Squamous metaplasia of PA is an unusual finding and has the possibility for misdiagnosis as squamous cell carcinoma (SCC). This study presents two cases of nasopharyngeal PA diagnosed as SCC from frozen sections, whereas permanent pathology was PA with squamous metaplasia. Preoperative endoscopy, radiographic images, and histopathological findings were reviewed. Two male patients underwent complete en-bloc resection of tumors with adequate margins because of the possibility of SCC from frozen section. The pathologic results were PA with squamous metaplasia and there was no recurrence during one year follow-up period. Nasopharyngeal PA can mimic SCC, surgeons should consider the clinical and radiological characteristics of tumors. We do not recommend deciding treatment modalities for nasopharyngeal tumors with only the frozen section.
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KEYWORD
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Nasopharyngeal neoplasm, Metaplasia, Pleomorphic adenoma
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